Oral GLP-1 Options:
Pill-Based Weight Loss

Open Water Rx offers three compounded oral GLP-1 options: oral semaglutide, oral tirzepatide, and a semaglutide + tirzepatide combination. Listed product and supply pricing is shown before payment — oral semaglutide 1 month $259 · 3 months $765 · 6 months $1,500; oral tirzepatide 1 month $298 · 3 months $888 · 6 months $1,759; semaglutide + tirzepatide combination 1 month $365 · 3 months $1,005 · 6 months $1,895. You select your preferred product and supply, and a licensed provider reviews your selection and prescribes only if medically appropriate. Availability varies by state.

Oral and injectable treatments use different formulations and dosing instructions. You select your preferred available product; a licensed provider reviews your selection and prescribes only if medically appropriate. Follow the directions supplied with your prescription.

Oral options avoid injections. Administration, food timing and storage instructions depend on the dispensed formulation. Follow your prescription label and pharmacy instructions.

Switching between formulations requires a provider review and a new prescription. Your licensed provider will assess whether an oral formulation is clinically appropriate based on your response to current therapy, side effect profile, and treatment goals. Any medication change must be supervised to ensure proper dosing and safety. Contact our support team to discuss a potential switch.

Yes. FDA-approved oral options include Wegovy tablets (semaglutide) and Foundayo (orforglipron) for weight management in eligible adults, and Rybelsus (semaglutide) for type 2 diabetes. Foundayo is not tirzepatide. These approvals apply to the specific manufactured products, not compounded oral or sublingual formulations. The brand references here explain treatment options; they do not mean Open Water Rx supplies those brands. Through Open Water Rx, any oral GLP-1 medication would be prepared by a licensed pharmacy for individual patients when a licensed provider determines it is clinically appropriate.

No. Wegovy® and Ozempic® are FDA-approved brand-name medicines containing semaglutide. Compounded semaglutide may be prepared by a licensed pharmacy pursuant to an individual prescription, but it is not a generic version of the brand medicines, and is not represented as bioequivalent, clinically equivalent, or interchangeable.

No. Zepbound® and Mounjaro® are FDA-approved brand-name medicines containing tirzepatide. Compounded tirzepatide may be prepared by a licensed pharmacy pursuant to an individual prescription, but it is not a generic version of the brand medicines, and is not represented as bioequivalent, clinically equivalent, or interchangeable.

Pricing is listed per product and supply before payment — no insurance required. Oral semaglutide 1 month $259 · 3 months $765 · 6 months $1,500; oral tirzepatide 1 month $298 · 3 months $888 · 6 months $1,759; semaglutide + tirzepatide combination 1 month $365 · 3 months $1,005 · 6 months $1,895. Each supply reflects the total price for that prepaid term. Compounded injectable semaglutide starts at $169/month, and shipping is included if prescribed.