Start your GLP-1 weight loss program online
A licensed provider reviews every case, medication is included if prescribed, and shipping is free. One flat monthly price — no insurance, no membership fees, no surprise checkout.
Open Water Rx is an online telehealth service for GLP-1 weight loss. Compounded semaglutide is $169/month and compounded tirzepatide is $219/month, with provider review, medication, and shipping included if prescribed. There is no insurance requirement, and nothing is charged unless a licensed provider approves treatment.
Intake takes about 5 minutes. Nothing is charged unless a licensed provider approves your medication. Not everyone qualifies.
Pick your program and start
One flat monthly price. Provider review, medication, and shipping included if prescribed.
Semaglutide
Once-weekly injection
$169
/mo
Tirzepatide
Once-weekly injection
$219
/mo
Oral Semaglutide
Daily tablet
$259
/mo
Secure intake · No charge unless approved · Cancel anytime
Quick Answers
The essentials, before you start
The questions people ask most before enrolling — answered plainly, with the numbers upfront.
How much does it cost to start?
One flat monthly price — no membership fee and no separate provider fee. Compounded semaglutide is $169/month and compounded tirzepatide is $219/month, medication and shipping included if prescribed.
Do I need insurance?
No. Open Water Rx does not require or bill insurance. The price you see is the price you pay, with no prior authorizations or claim denials.
How fast can I start?
The online intake takes about 5 minutes. A licensed provider typically reviews your case within 1–2 business days, and medication ships shortly after if prescribed.
What if I'm not approved?
You are not charged. Nothing is charged unless your medication is approved by a licensed provider. If treatment is not clinically appropriate, there is no cost.
Do I need an in-person visit?
No. Open Water Rx is fully online. In most states the provider review is asynchronous — no clinic visit, phone call, or video appointment required.
Can I cancel anytime?
Yes. There is no long-term commitment and no cancellation fee. You can cancel through your patient portal at any time, with no advance notice required.
Choose Your Program
Three ways to start
Every program is reviewed by an independent licensed provider and prescribed only when clinically appropriate. Pick one to begin — you can discuss the best fit with your provider during review.
Compounded Semaglutide
Once-weekly injection · Single GLP-1 pathway
The most widely prescribed starting point for GLP-1 therapy. A single-ingredient option with years of clinical data behind it.
- Licensed provider review included
- Medication included if prescribed
- Discreet shipping included if prescribed
- Ongoing dosing support
Best for: First-time GLP-1 patients who want the most established option.
Start with SemaglutideCompounded Tirzepatide
Once-weekly injection · Dual GIP + GLP-1 pathway
Activates two metabolic pathways at once. Many patients choose this when they want a stronger dual-action option.
- Licensed provider review included
- Medication included if prescribed
- Discreet shipping included if prescribed
- Ongoing dosing support
Best for: Patients weighing two-pathway support or plateauing on semaglutide.
Start with TirzepatideCompounded Oral Semaglutide
Daily tablet · No injections
A daily tablet for anyone who would rather not use an injection. Same clinician-guided process, needle-free.
- Licensed provider review included
- Medication included if prescribed
- Discreet shipping included if prescribed
- Ongoing dosing support
Best for: Patients who prefer a non-injectable, needle-free routine.
Start with Oral SemaglutideFlat monthly pricing with no membership fee and no separate provider fee. Medication and shipping are included if prescribed. Final treatment decisions are made by an independent licensed provider; not all patients qualify.
How Starting Works
Four steps from intake to your door
No waiting room, no insurance battle, no hidden steps. Here is exactly what happens after you click start.
- 01
Right now · under 2 min
Pick your program
Choose semaglutide, tirzepatide, or oral semaglutide. Not sure? The provider can recommend the best fit based on your health profile.
- 02
About 5 minutes
Complete your online intake
Answer a short, secure set of health questions from any device, 24/7. No appointment and no waiting room.
- 03
Typically 1–2 business days
Licensed provider review
An independent licensed provider reviews your history and decides whether treatment is clinically appropriate for you.
- 04
Shortly after approval
Treatment ships if prescribed
If you're approved, medication ships discreetly from a licensed pharmacy partner — free shipping, straight to your door.
Transparent Pricing
See every cost before you commit. No surprises, ever.
Program pricing is shown clearly before checkout. Semaglutide $169/mo, tirzepatide $219/mo, oral semaglutide $259/mo — flat pricing with no membership or provider fees. Longevity and men's health programs have their own transparent pricing. No insurance required, no hidden fees.
Full cost disclosed before you begin
Every program displays its complete price upfront. Weight-loss programs: semaglutide $169/mo, tirzepatide $219/mo. No hidden fees, no surprise charges after checkout. What you see is what you pay.
No insurance required, and that's a feature
By not accepting insurance, we eliminate prior authorization delays, coverage disputes, and surprise out-of-network bills. One clear price covers your full care cycle. Because Open Water Rx does not bill insurance, your care is not submitted to an insurer by Open Water Rx.
All-inclusive, every month
Your program price covers provider review, prescription if clinically appropriate, pharmacy preparation, discreet shipping, and ongoing follow-up care. Optional add-on services are always clearly priced and never required.
Why Open Water Rx
A simpler, more transparent way to start
Clinician-guided GLP-1 care without the waiting rooms, insurance disputes, or hidden line items.
Flat, all-inclusive pricing
One monthly price covers provider review, medication if prescribed, shipping, and ongoing support. No membership fee, no separate provider fee.
No insurance required
Skip the prior authorizations and claim denials. Cash-pay means the price you see is the price you pay.
Nothing charged unless approved
You are not charged unless a licensed provider approves your treatment. If it isn't clinically appropriate, you pay nothing.
Independent licensed providers
Every case is reviewed by an independent, licensed U.S. medical provider — never an automated approval.
Licensed U.S. pharmacies
Compounded medication is prepared by independent, licensed U.S. compounding pharmacies operating under federal and state law.
Start today, from anywhere
Nationwide telehealth for eligible patients in all 50 states. No clinic visit, no commute, no waiting room.
“I lost 30 lbs as well and feel like myself again. Within a couple hours of signing up, I got my telehealth doctor's phone call.”
Verified Google review
FAQ
Starting your program, answered
Pick a program and complete a short online health intake — it takes about five minutes and is available 24/7. An independent licensed provider then reviews your case, typically within one to two business days. If treatment is clinically appropriate, your prescription is filled by a licensed pharmacy and ships discreetly to your door.
One flat monthly price covers everything. Compounded semaglutide is $169/month and compounded tirzepatide is $219/month — medication, provider review, and shipping included if prescribed. There is no membership fee and no separate provider fee. Oral semaglutide is $259/month.
No. Open Water Rx is cash-pay and does not require or bill insurance. That removes prior authorizations, claim denials, and surprise out-of-network bills. Everything is shown before you pay.
No. Nothing is charged unless a licensed provider approves your medication. If the provider determines treatment is not clinically appropriate for you, you are not charged.
In most states, no. Open Water Rx is a fully online telehealth service, and the provider review is usually asynchronous — no clinic visit, phone call, or webcam appointment. A small number of states require a brief synchronous visit, and we will let you know if that applies to you.
Semaglutide is a single-ingredient GLP-1 receptor agonist. Tirzepatide is a dual GIP/GLP-1 agonist that activates two metabolic pathways at once and may produce greater average weight loss for some patients. A licensed provider will recommend the best option based on your individual health profile.
After your intake, provider review typically takes one to two business days. If you are approved, medication ships shortly after from a licensed compounding pharmacy. Many patients receive their medication within about a week, though timing can vary.
Yes. There is no long-term commitment and no cancellation fee. You can cancel through your patient portal at any time, with no advance notice required. Orders are nonrefundable once the pharmacy has processed the item.
No. Compounded semaglutide and compounded tirzepatide are not FDA-approved finished drug products. They are prepared by independent, licensed compounding pharmacies pursuant to an individual prescription when a licensed provider determines it is clinically appropriate. They are not generic versions of any brand-name medicine and are not represented as interchangeable.
GLP-1 medications may not be appropriate for people with a personal or family history of medullary thyroid carcinoma, Multiple Endocrine Neoplasia syndrome type 2, pancreatitis, or certain other conditions. A licensed provider reviews your full health history before any prescribing decision. Not everyone qualifies.
Ready to start?
Your intake takes 5 minutes.
Begin a secure online intake and see whether GLP-1 treatment may be appropriate for you. A licensed provider reviews every case — and nothing is charged unless you're approved.
No charge unless approved. No charge if not eligible. Cancel anytime — no long-term commitment.
Not ready to enroll? Check your eligibility first — it takes 2–3 minutes and there is no obligation.
Important FDA Notice: Compounded semaglutide and tirzepatide are not FDA-approved finished drug products. All prescribing decisions are made by independent licensed medical providers. A valid patient-provider relationship must be established before any prescription is issued. Open Water Rx does not manufacture, compound, or dispense medications. Read full consent →
Medical References
Sources & Clinical Evidence
Published by
Open Water Rx
STEP 1 Trial (NEJM, 2021)
Wilding JPH et al. Once-weekly semaglutide 2.4mg in adults with overweight or obesity. New England Journal of Medicine 2021;384:989-1002.
View source
SURMOUNT-1 Trial (NEJM, 2022)
Jastreboff AM et al. Tirzepatide once weekly for the treatment of obesity. New England Journal of Medicine 2022;387:205-216.
View source
FDA: Human Drug Compounding
Official FDA guidance on 503A compounding pharmacy regulations and drug shortage policy. U.S. Food & Drug Administration.
View source
FDA Drug Shortages Database
Current drug shortage status for all medications including semaglutide and tirzepatide. U.S. Food & Drug Administration.
View source
FTC: Health Claims Guidance
Federal Trade Commission guidance on substantiating health claims in advertising and marketing materials.
View source
FDA Disclosure: Compounded medications are not FDA-approved finished drug products and have not been evaluated by the FDA for safety, efficacy, or quality in the same manner as commercially approved drugs. Clinical trial data cited above refers to FDA-approved formulations studied in controlled trials — not compounded medications. Individual results vary and are not guaranteed. Open Water Rx does not manufacture, compound, or dispense medications. Read full telehealth consent →