Important: Compounded semaglutide and tirzepatide are not FDA-approved drug products. Pricing and availability are subject to clinical appropriateness and regulatory change. Prescriptions are issued only when an independent licensed physician determines individual clinical appropriateness. Read full consent →

Compounded semaglutide starts at $249/month and tirzepatide starts at $339/month through Open Water Rx. Both prices are all-inclusive: physician review, prescription if approved, free shipping, and ongoing support. No separate medication charge.
Semaglutide
$249/mo
All-inclusive
Tirzepatide
$339/mo
All-inclusive
No commitment required · No insurance needed · Serving all of Florida
All-Inclusive Pricing
Every Open Water Rx plan is all-inclusive. The price you see is the price you pay. No separate medication charge, no shipping fee, no consultation fee.
Physician review
Board-certified Florida physician reviews your case within 24 to 48 hours.
Prescription if approved
Personalized prescription issued through a licensed, FDA-registered compounding pharmacy.
Free monthly shipping
Your medication ships free to any Florida address every month. No shipping charge ever.
Ongoing support
Secure patient messaging, monthly check-ins, and dosage guidance throughout your treatment.
Base labs when appropriate
Baseline lab work included when clinically appropriate at your physician's discretion.
Transparent pricing
No setup fee, no consultation fee, no cancellation fee. Cancel anytime.
Save up to $1,000+ per month vs. retail pharmacy pricing
Retail Wegovy costs approximately $1,300/month without insurance. Open Water Rx compounded semaglutide starts at $249/month, all-inclusive. That is a potential saving of over $1,000 per month for the same active ingredient.
$1,000+
Saved per month
vs. retail Wegovy
Cost Comparison
Retail pharmacy prices are based on publicly available information as of early 2026 without insurance. Individual costs may vary.
| Option | Monthly Cost |
|---|---|
Compounded Semaglutide (Open Water Rx) Open Water Rx | $249 |
Compounded Tirzepatide (Open Water Rx) Open Water Rx | $339 |
Wegovy (retail pharmacy, no insurance) | ~$1,300 |
Ozempic (retail pharmacy, no insurance) | ~$900 |
Zepbound (retail pharmacy, no insurance) | ~$1,000 |
National telehealth platform (typical) | $350 to $500+ |
Retail pharmacy prices are approximate and based on publicly available information as of early 2026 without insurance. Compounded semaglutide and tirzepatide are not FDA-approved products. Individual costs may vary.
Our Plans
Two medications. Two plans. One all-inclusive price. Your physician recommends the right fit based on your health profile.
Semaglutide Plan
Prepaid plans may lower the effective monthly rate
Lock in early-access savings. No commitment.
Tirzepatide Plan
Prepaid plans may lower the effective monthly rate
Lock in early-access savings. No commitment.
FAQ
Everything you need to know about the cost of semaglutide and tirzepatide in Florida in 2026.
Through Open Water Rx, compounded semaglutide starts at $249/month. This is an all-inclusive price covering physician review, prescription if approved, free monthly shipping, and ongoing support. No separate medication charge. Some longer-term prepaid plans may lower the effective monthly rate.
Through Open Water Rx, compounded tirzepatide starts at $339/month. This is an all-inclusive price covering physician review, prescription if approved, free monthly shipping, and ongoing support. No separate medication charge. Some longer-term prepaid plans may lower the effective monthly rate.
Retail Wegovy costs approximately $1,300/month and Ozempic approximately $900/month without insurance. Compounded semaglutide is prepared by independent, FDA-registered compounding pharmacies using the base active pharmaceutical ingredient (API), which is significantly less expensive than the branded finished drug product. The cost difference reflects the absence of brand-name markup, not a difference in the active ingredient itself. Compounded semaglutide is not FDA-approved and is not the same as or interchangeable with any FDA-approved product.
Most insurance plans do not cover GLP-1 medications prescribed solely for weight loss. Coverage for type 2 diabetes indications varies by plan. Open Water Rx does not accept insurance. Our pricing is transparent and all-inclusive: semaglutide from $249/month, tirzepatide from $339/month. No prior authorizations, no insurance battles.
Both plans include: physician review by a board-certified Florida physician, prescription if clinically approved, compounded medication from a licensed FDA-registered pharmacy, free monthly shipping to your Florida address, and ongoing support including secure patient messaging. No separate medication charge. Transparent, all-inclusive pricing.
Open Water Rx offers some of the most competitive all-inclusive pricing for physician-supervised GLP-1 therapy in Florida. Some online platforms advertise lower prices but charge separately for physician consultations, shipping, or medication. Always compare total monthly cost, not just the advertised plan fee. Our $249 and $339 prices are fully all-inclusive.
Yes. Some longer-term prepaid plans may lower the effective monthly rate compared to month-to-month pricing. Details are provided during the enrollment process. There is no obligation to commit to a longer plan.
No. There is no separate consultation fee, setup fee, or enrollment fee. The monthly plan price is all-inclusive. If a prescription is not issued following your evaluation, a refund may be considered on a case-by-case basis at our discretion. Contact members@openwaterrx.com within 7 days of the charge.
Open Water Rx pricing is competitive with or lower than major national GLP-1 telehealth platforms, with the added benefit of Florida-based board-certified physicians (not NPs or PAs), free shipping included in the plan price, and direct physician access. National platforms may charge separately for consultations, shipping, or medication. Always compare total all-in monthly cost.
Compounding availability is subject to FDA shortage status and regulatory change. If the FDA removes a drug from the shortage list, compounding of that drug may become subject to additional restrictions. Open Water Rx will make reasonable efforts to notify affected patients of any such changes. Pricing and availability are always subject to clinical appropriateness and regulatory change.
Related pages
Semaglutide in Florida
Full guide to compounded semaglutide: how it works, eligibility, and how to get a prescription online.
Tirzepatide in Florida
Full guide to compounded tirzepatide: dual GIP/GLP-1 mechanism, 20 to 22% avg weight loss, from $339/mo.
Semaglutide vs Tirzepatide
Side-by-side comparison of both medications: efficacy, cost, side effects, and who each is best for.
Join the waitlist and lock in exclusive early-access savings. Semaglutide from $249/month, tirzepatide from $339/month. All-inclusive. No commitment required.
Join the Waitlist and Unlock SavingsCompounded semaglutide and tirzepatide are not FDA-approved products. Pricing and availability are subject to clinical appropriateness and regulatory change.
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Physician review within 48 hrs · Free shipping · Semaglutide from $249/mo · Tirzepatide from $339/mo
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