
Open Water Rx accepts patients in all 50 states. Compounded semaglutide $249/mo · Tirzepatide $339/mo. 100% online. No insurance required. Delivered free to your door.
Free to join · No commitment required
50
States accepting patients
$249
Starting price, semaglutide
100%
Online, no clinic visit in most cases
15–22%
Avg. weight loss in clinical trials*
*Clinical trial averages. Individual results vary and are not guaranteed. Compounded medications are not approved finished drug products.
Direct Answer
Yes. Open Water Rx is a 100% telehealth GLP-1 weight loss platform accepting patients in all 50 states. Complete a 5-minute health evaluation online. No clinic visit required in most cases. A licensed medical provider reviews your case and if approved, your compounded semaglutide or tirzepatide ships free to your door. Semaglutide starts at $249/month, tirzepatide starts at $339/month. No insurance required.
City Directory
Select your city for a dedicated landing page with local SEO, city-specific FAQs, and direct enrollment. Don't see your city? We still serve your state. Start your program below.
Cape Coral
Lee County
Fort Myers
Lee County
Naples
Collier County
Bonita Springs
Lee County
Sarasota
Sarasota County
Tampa
Hillsborough County
Orlando
Orange County
Miami
Miami-Dade County
Boca Raton
Palm Beach County
Jacksonville
Duval County
Clearwater
Pinellas County
Bradenton
Manatee County
Port Charlotte
Charlotte County
Estero
Lee County
Marco Island
Collier County
St. Petersburg
Pinellas County
Venice
Sarasota County
Punta Gorda
Charlotte County
Englewood
Sarasota County
Gainesville
Alachua County
Tallahassee
Leon County
West Palm Beach
Palm Beach County
Pembroke Pines
Broward County
Hialeah
Miami-Dade County
Pensacola
Escambia County
Lakeland
Polk County
Palm Bay
Brevard County
Pompano Beach
Broward County
Daytona Beach
Volusia County
Fort Lauderdale
Broward County
Houston
Harris County
Dallas
Dallas County
San Antonio
Bexar County
Austin
Travis County
Fort Worth
Tarrant County
Plano
Collin County
Frisco
Collin County
The Woodlands
Montgomery County
Sugar Land
Fort Bend County
Katy
Harris County
McKinney
Collin County
Irving
Dallas County
Arlington
Tarrant County
Round Rock
Williamson County
Denton
Denton County
New York
New York County
New York City
New York County
Manhattan
New York County
Brooklyn
Kings County
Queens
Queens County
Bronx
Bronx County
Staten Island
Richmond County
Long Island
Nassau County
Hempstead
Nassau County
Garden City
Nassau County
Great Neck
Nassau County
Roslyn
Nassau County
Huntington
Suffolk County
Syosset
Nassau County
Jericho
Nassau County
Oyster Bay
Nassau County
Melville
Suffolk County
Mineola
Nassau County
Westbury
Nassau County
White Plains
Westchester County
Yonkers
Westchester County
Scarsdale
Westchester County
Rye
Westchester County
New Rochelle
Westchester County
Mount Vernon
Westchester County
Albany
Albany County
Saratoga Springs
Saratoga County
Buffalo
Erie County
Rochester
Monroe County
Syracuse
Onondaga County
Ithaca
Tompkins County
Binghamton
Broome County
Poughkeepsie
Dutchess County
Kingston
Ulster County
Newburgh
Orange County
Chicago
Cook County
Naperville
DuPage & Will County
Aurora
Kane & DuPage County
Joliet
Will County
Schaumburg
Cook County
Evanston
Cook County
Oak Park
Cook County
Arlington Heights
Cook County
Orland Park
Cook County
Tinley Park
Cook County
Downers Grove
DuPage County
Hinsdale
DuPage County
Elmhurst
DuPage County
Glenview
Cook County
Northbrook
Cook County
Highland Park
Lake County
Lake Forest
Lake County
Winnetka
Cook County
Wilmette
Cook County
Skokie
Cook County
Des Plaines
Cook County
Park Ridge
Cook County
Palatine
Cook County
Barrington
Lake & Cook County
Wheaton
DuPage County
Glen Ellyn
DuPage County
Bolingbrook
Will County
Plainfield
Will County
Bloomington
McLean County
Normal
McLean County
Peoria
Peoria County
Springfield
Sangamon County
Champaign
Champaign County
Urbana
Champaign County
Rockford
Winnebago County
Don't see your city or state listed above?
No problem. Open Water Rx accepts patients in all 50 states. City-specific pages are added regularly. In the meantime, start your enrollment and your licensed provider will take care of the rest.
Works Everywhere
Complete Evaluation
5-min online form, 24/7, any device, any state
Provider Reviews
Independent licensed provider in your state
Prescription Issued
Compounded semaglutide or tirzepatide
Shipped to Your Door
Free delivery anywhere in the US
Some states may require a synchronous initial visit. Availability varies by state. Compounded medications are not approved finished drug products.
Nationwide Coverage
Open Water Rx is a fully online telehealth platform connecting patients with independent licensed medical providers for GLP-1 weight loss therapy across all 50 United States and Washington, D.C. Our nationwide model eliminates the need for in-person clinic visits in most states, allowing patients from rural Alaska to urban Florida to access the same high-quality clinician-guided weight management programs. Compounded semaglutide starts at $249 per month and compounded tirzepatide starts at $339 per month — prices that include licensed provider review, medication if prescribed, shipping if prescribed, and ongoing support. No insurance is required.
The process begins with a brief, secure online health evaluation that takes approximately five minutes. Patients answer questions about their medical history, current medications, weight loss goals, and any contraindications. An independent licensed medical provider then reviews this information asynchronously — meaning there is no need to schedule an appointment or wait on hold. In most states, the provider can issue a prescription directly through our platform if treatment is clinically appropriate. The prescription is sent to one of our licensed, FDA-registered compounding pharmacy partners, which prepares the medication and ships it discreetly to the patient's door at no additional shipping cost.
Some states have enacted stricter telehealth prescribing laws that require a synchronous interaction — typically a brief live video visit — before a provider can issue a prescription for certain medications. These states include, but may not be limited to, those with enhanced controlled substance or weight management prescribing regulations. When you begin your intake, our platform automatically detects your state's requirements and guides you through scheduling a HIPAA-compliant video visit with a provider licensed in your state. This video visit is included in your program at no extra charge. Even in states requiring video visits, the overall process remains far more convenient than traditional in-person weight loss clinics, with no driving, no waiting rooms, and no taking time off work.
Access licensed provider review from home without visiting a physical clinic or weight loss center
Same all-inclusive pricing in every state — $249/month semaglutide, $339/month tirzepatide starting prices
Discreet shipping to any U.S. address with plain packaging and no pharmacy branding
Ongoing async provider support with secure messaging for questions and dose adjustments
No insurance required, no prior authorizations, no pharmacy discount cards needed
State-credentialed providers ensure compliance with local telehealth regulations
Compounded semaglutide and tirzepatide are prepared by licensed compounding pharmacies operating under Section 503A or 503B of the Federal Food, Drug, and Cosmetic Act. These are not FDA-approved finished drug products and are not interchangeable with brand-name products like Ozempic, Wegovy, or Zepbound. The active pharmaceutical ingredient — semaglutide or tirzepatide — is the same molecule used in clinical trials that demonstrated 15 to 22.5 percent average body weight loss, but the compounded formulation, delivery device, and inactive ingredients may differ from brand-name versions.
Compounding pharmacies must meet rigorous quality standards including FDA registration, USP <797> sterile compounding guidelines, and state board of pharmacy oversight. Open Water Rx partners exclusively with licensed, FDA-registered compounding pharmacies that maintain these standards. Every prescription is issued only when an independent licensed provider determines there is a valid individual clinical reason based on the patient's complete health evaluation.
Patients frequently ask whether compounded GLP-1 medications are legal in their state. The answer is yes — in all 50 states, licensed medical providers may prescribe compounded medications when they determine such treatment is clinically appropriate for an individual patient. Telehealth prescribing of non-controlled substances like GLP-1 agonists is legal nationwide, subject only to state-specific requirements around synchronous versus asynchronous initial evaluations.
Open Water Rx maintains dedicated city landing pages for major metropolitan areas across the United States, providing localized information about GLP-1 weight loss telehealth availability, nearby provider coverage, and state-specific telehealth requirements. Our city directory includes pages for Florida (Cape Coral, Fort Myers, Naples, Tampa, Orlando, Miami, and more), Texas (Dallas, Houston, Austin, San Antonio), California (Los Angeles, San Diego, San Francisco), New York, Illinois, Arizona, Georgia, North Carolina, and additional states added regularly. Each city page includes local SEO optimization, city-specific FAQs, and direct enrollment links.
If you do not see your specific city listed, this does not affect your eligibility. Open Water Rx accepts patients in every city, town, and rural area in all 50 states. The city pages are an additional resource for patients who prefer localized information; they are not a requirement for enrollment. Start your program today regardless of your location, and your licensed provider will ensure you receive care compliant with your state's specific telehealth regulations.
Telehealth Regulations
Telehealth regulations for prescription medications vary by state, and Open Water Rx is fully compliant with all applicable federal and state laws governing remote medical care. While the majority of states allow fully asynchronous (online-only) initial evaluations for GLP-1 weight loss prescriptions, some states have enacted specific requirements that mandate a synchronous interaction — typically a brief live video visit — before a licensed provider can issue a prescription for certain medication categories.
States with stricter telehealth prescribing requirements may include, but are not limited to, those with enhanced controlled substance regulations or specific rules around weight management medications. During your intake process, our platform automatically identifies your state's requirements and guides you through any necessary steps, including scheduling a brief video consultation with an independent licensed provider credentialed in your state. These video visits are conducted through our HIPAA-compliant telehealth infrastructure and are included in your program price at no additional charge.
Regardless of your state's specific requirements, every Open Water Rx patient receives the same standard of care: an independent licensed medical provider reviews your complete health history, determines clinical appropriateness on an individual basis, and provides ongoing follow-up throughout your program. All 50 states and Washington D.C. are served. Your specific state's telehealth requirements will be clearly communicated before you begin your evaluation.
Most states allow complete online evaluation and prescribing without a live video visit. Your provider reviews your health history asynchronously and issues a prescription if clinically appropriate.
Some states require a brief synchronous video consultation before initial prescribing. This visit is scheduled automatically during intake and is included in your plan at no extra cost.
Every provider on our platform is independently licensed and credentialed in the specific states where they practice. You always work with a provider legally authorized to treat patients in your state.
Transparent Pricing
Semaglutide
GLP-1 receptor agonist
15–17% avg. weight loss · STEP 1 trial
Tirzepatide
Dual GIP + GLP-1 agonist
20–22.5% avg. weight loss · SURMOUNT-1 trial
All-inclusive pricing: provider review, prescription if approved, free shipping, ongoing support. No insurance required. Individual results vary. Compounded medications are not approved finished drug products.
Wherever you are in the US, we're here. Semaglutide $249/mo · Tirzepatide $339/mo. Start online today. No insurance. No clinic visit in most cases.
Start Your ProgramNationwide Network
Open Water Rx has built a nationwide telehealth infrastructure that connects patients with independent licensed medical providers credentialed in their specific states. This state-by-state provider network ensures that every patient receives care from a clinician legally authorized to practice in their jurisdiction, while our unified technology platform delivers a consistent, high-quality experience regardless of location. Our network includes providers licensed in all 50 states and Washington, D.C., with particular concentration in high-demand markets including Florida, Texas, California, New York, Illinois, Arizona, Georgia, and North Carolina.
The logistics of nationwide medication fulfillment are managed through partnerships with multiple licensed compounding pharmacies strategically located across the United States. This distributed pharmacy network reduces shipping times, ensures compliance with state-specific pharmacy regulations, and provides redundancy in case of supply chain disruptions. All pharmacy partners are FDA-registered and operate under either Section 503A (traditional compounding for individual patients) or Section 503B (outsourcing facilities) of the Federal Food, Drug, and Cosmetic Act.
For patients in states with stricter telehealth prescribing requirements, our platform automatically schedules synchronous video visits with providers licensed in those states. These visits are conducted through our HIPAA-compliant video infrastructure and are included in the program price at no additional cost. Even in states requiring video visits, the overall experience remains significantly more convenient than traditional in-person care, with no travel, no parking, and no waiting rooms. Patients simply log in at their scheduled time and speak directly with their provider from any private location.
Independent licensed providers credentialed in all 50 states and D.C. Every patient is matched with a provider authorized to practice in their state.
Licensed FDA-registered compounding pharmacies strategically located across the US for fast, compliant medication fulfillment and shipping.
Our platform automatically detects your state, identifies applicable telehealth requirements, and guides you through the appropriate intake path.
Open Water Rx maintains dedicated city landing pages and localized content for major metropolitan areas across the United States. Our most active service areas include Florida (Cape Coral, Fort Myers, Naples, Tampa, Orlando, Miami, Jacksonville, St. Petersburg, Hialeah, Tallahassee), Texas (Dallas, Houston, Austin, San Antonio, Fort Worth), California (Los Angeles, San Diego, San Francisco, San Jose, Sacramento), New York (New York City, Buffalo, Rochester, Yonkers), Illinois (Chicago, Aurora, Naperville, Joliet), Arizona (Phoenix, Tucson, Mesa, Scottsdale), Georgia (Atlanta, Augusta, Columbus, Savannah), and North Carolina (Charlotte, Raleigh, Greensboro, Durham). We also serve patients in all smaller cities, towns, and rural communities in these and all other states.
If you do not see your specific city listed on our city directory, this does not affect your eligibility or access to care. City-specific pages are an additional resource for patients who prefer localized information; they are not a requirement for enrollment. Start your program today regardless of your location, and your licensed provider will ensure you receive care fully compliant with your state's telehealth regulations.
Semaglutide $249/mo · Tirzepatide $339/mo · No insurance required · Shipping included if prescribed
GLP-1 $249/mo · No insurance
Free to start · No hidden fees